Description
Product Characteristics:
Calcium-dependent NADPH oxidase that generates superoxide. Also functions as a calcium-dependent proton channel and may regulate redox-dependent processes in lymphocytes and spermatozoa. May play a role in cell growth and apoptosis.
Subcellular location: Cytoplasm, Cell membrane
Synonyms: NADPH oxidase 5, NADPH oxidase EFhand calcium binding domain 5, NOX5, NOX5_HUMAN, MGC149776, MGC149777.
Target Information: This gene is predominantly expressed in the testis and lymphocyte-rich areas of spleen and lymph nodes. It encodes a calcium-dependen NADPH oxidase that generates superoxide, and functions as a calcium-dependent proton channel that may regulate redox-dependent processes in lymphocytes and spermatozoa. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]